Enter dates to see availability

From USD 185 per night
Check-in 15 Nov 2026
Check-out 16 Nov 2026
Guests 2 guests

Adults:

2

Children:

0
All rates verified
How we verified prices Our team regularly checks prices to make sure you see the lowest available rates. We compare them with hotel prices and other providers. If discounts or promotions appear, prices on our site are updated accordingly.

Hilton Jacksonville At Mayo Clinic Near Beaches

4745 Transformation Way, Southpoint-Butler Blvd, Jacksonville, United States - Near Mayo Clinic
8.8/10 · 143 reviews

The comfortable 4-star Hilton Jacksonville At Mayo Clinic hotel lies in the business area of Jacksonville, 2.9 miles from natural attractions such as Cradle Creek Preserve. Located in the Southpoint-Butler Blvd district of Jacksonville, this Jacksonville hotel offers 252 rooms along with a year-round outdoor swimming pool.

Location

Nestled around a 10-minute drive from Go Tuk'n, the hotel is around a 15-minute drive from Jacksonville Beach Pier. Adventure Landing Jacksonville Beach is also located 2.6 miles from the Hilton Jacksonville At Mayo Clinic. The nearby family attractions include Mind Bender Escape Rooms about 20 minutes by car from the accommodation. This hotel is located in Jacksonville, within 15 miles of Union train station.

Rooms

The rooms are equipped with coffee/tea making facilities, along with a flat-screen TV with satellite channels for guests' comfort. Providing a roll-in shower and a sink, some bathrooms have towels.

Food & Drinks

The American Coastal Kitchen restaurant serves American food. Guests can enjoy the in-house bar on premises.

Leisure & Activities

Hilton Jacksonville At Mayo Clinic hotel provides guests with access to fitness classes in a fitness club.

Why choose Hilton Jacksonville At Mayo Clinic Near Beaches

Select room
  • Outdoor swimming pool available

  • Fitness center for workouts

  • In-house dining options available

  • 24-hour front desk service

Main amenities

  • Wi-Fi

  • 24-hour services

  • Express check-in/ -out

  • Swimming Pool

  • Fitness/Gym

  • On-site Dining

  • Meeting facilities

  • Child-friendly

  • Wheelchair access

  • Breakfast

  • Air conditioning

  • Pets

General
  • Wi-Fi
  • 24-hour services
  • Express check-in/ -out
  • Swimming Pool
  • Fitness/Gym
  • On-site Dining
  • Meeting facilities
  • Child-friendly
  • Wheelchair access
  • Breakfast
  • Air conditioning
  • Pets
1/28

Internet

  • Wi-Fi

Parking options

  • Parking

Activities

  • Fitness centre

Property services

  • Safe deposit box
  • 24-hour reception
  • Express check-in/-out
  • Security
  • Room service
  • Housekeeping
  • Laundry
  • Dry cleaning
  • Shops/Commercial services
  • Welcome drink

Dining options

  • In-room breakfast
  • Restaurant
  • Bar/Lounge area

Business facilities

  • Business centre
  • Meeting/Banquet facilities
  • Fax/Photocopying

For kids

  • Cots
  • Children's buffet

Recreation

  • Outdoor swimming pool
  • Beach umbrellas
  • Sun loungers
  • Sun terrace
  • Leisure/TV room

For disabled guests

  • Rooms/Facilities for disabled
  • Wheelchair access
  • Toilet for disabled
  • Bathroom for disabled

In the rooms

  • Air conditioning
  • Heating
  • Terrace
  • Garden furniture
  • Tea and coffee facilities
  • Ironing facilities

In the bathroom

  • Free toiletries
  • Sink

Devices

  • Flat-screen TV
  • AM/FM alarm clock

Design

  • Curtains

General facilities

  • No smoking on site
  • Lift
  • ATM/Cash machine
  • Fireplace
  • Smoke detectors
  • Electric vehicle charging station
  • Fire extinguishers
  • Key card access

Pets

  • Pets allowed

Important information

Check-in:
from 16:00 until 23:59
Check-out:
until 11:00

Rooms

Current offers Editor's Pick
Up to 15% off

Longer Stays

A few extra nights let you slow down, find favorite spots, and experience the place beyond the highlights.
Up to 10% off

Mobile Rates

Book in a few taps and save a little more for the places, tastes, and moments waiting throughout your stay.
Up to 20% off

Early Bird

Reserve while the right dates are open, then enjoy planning everything that comes after stress-free, step by step.

Photos of Hilton Jacksonville At Mayo Clinic Near Beaches

Location of Hilton Jacksonville At Mayo Clinic Near Beaches

4745 Transformation Way, Southpoint-Butler Blvd, Jacksonville, United States

 -  Near Mayo Clinic
Attractions
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Transportation

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    Guest reviews of Hilton Jacksonville At Mayo Clinic Near Beaches

    Based on ratings from trusted providers

    8.8 /10
    Fabulous 143 reviews
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          100% Verified Reviews
          Enter dates to see availability
          From USD 185 per night
          Check-in 15 Nov 2026
          Check-out 16 Nov 2026
          Guests 2 guests

          Adults:

          2

          Children:

          0
          All rates verified
          How we verified prices Our team regularly checks prices to make sure you see the lowest available rates. We compare them with hotel prices and other providers. If discounts or promotions appear, prices on our site are updated accordingly.
          Check-in & out
          15 Nov 2026
          —
          16 Nov 2026
          Guests
          2 guests
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          Important information
          Hilton Jacksonville At Mayo Clinic Near Beaches
          Check-in:
          from 16:00 until 23:59
          Check-out:
          until 11:00